Ever since Vincent Allfrey's pioneering studies in the early 1960s, we have known that histones are post-translationally modified 1. We now know that there are a large number of different histone post ...

A new mini-review outlines how epigenetic silencing of NK-activating ligands helps urothelial carcinoma evade immune attack ...

Large-scale mapping of chromatin features has emerged as a powerful tool to understand the global landscape of genome regulation. In particular, chromatin immunoprecipitation followed by sequencing ...

Penn State researchers found that cancer-linked BRD4 can bind nucleosomes through both DNA contacts and recognition of ...

Plant DNA viruses — including double-stranded DNA viruses such as caulimoviruses and single-stranded DNA viruses such as ...

In the "Amino Up Research Notes," we introduce the research themes that Amino Up is working on in an easy-to-understand way, ...

Aging alters DNA methylation, histone modifications, chromatin organization, and regulatory RNA activity, affecting gene ...

An epigenetic factor that is essential for producing mature egg cells in mice has been identified by RIKEN researchers for the first time. This discovery could aid research into cases of infertility ...

Hepatocellular carcinoma (HCC) cells undergo extensive metabolic reprogramming, including alterations in glucose, lipid, and amino acid metabolism, to ...

(A) DNA methylation is maintained by DNMT1 on hemimethylated DNA after replication, while DNMT3A/3B catalyse de novo methylation on unmethylated DNA. In mammals, this modification is primarily found ...