A genome-wide CRISPR screen identifies UGCG-driven sphingolipid metabolism and protective autophagy as drivers of Niraparib ...

Breast cancer (BC) remains the most prevalent cancer among women worldwide, presenting significant challenges due to its high incidence and mortality rates. Traditional treatments, such as ...

Application of the high-precision technique is part of a clinical trial to treat a genetic disease that can cause liver and ...

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily ...

WILMINGTON, DEL. (November 14, 2025) – In a major step forward for cancer care, researchers at ChristianaCare’s Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology ...

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments, including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily ...

Targeted CRISPR lipid nanoparticles eliminated 50% of tumors in mice with head and neck cancer. Researchers from Tel Aviv University (Israel), led by Razan Masarwy, have investigated utilizing CRISPR ...

Immunotherapeutic strategies have made huge strides in cancer treatment for many solid tumors over the past decade. But the promising results have failed to make a large change in the treatment of ...

In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in ...

The immune system plays a crucial role in fighting tumors and metastases. Consequently, it is decisive to conduct cancer research in mouse models with an immune system that is as natural as ...